Identification of homozygous haplotypes carrying putative recessive lethal mutations that compromise fertility traits in French Lacaune dairy sheep
نویسندگان
چکیده
منابع مشابه
Harmful recessive effects on fertility detected by absence of homozygous haplotypes.
Five new recessive defects were discovered in Holsteins, Jerseys, and Brown Swiss by examining haplotypes that had a high population frequency but were never homozygous. The method required genotypes only from apparently normal individuals and not from affected embryos. Genotypes from the BovineSNP50 BeadChip (Illumina, San Diego, CA) were examined for 58,453 Holsteins, 5,288 Jerseys, and 1,991...
متن کاملGenetIc evaluatIon for mIlk productIon traIts In slovakIan lacaune sheep
Selection for breeding animals as parents of next generation, based on genetic analyses of most important traits, became a standard for selection practices in most of the farm animal species in Slovakia. In this respect, about ten years of experience could be traced in Slovakian dairy cattle (Candrák et al., 1997) and pigs (Groeneveld and Peškovičová, 1999 and Peškovičová et. al., 1999). First ...
متن کاملNovel Harmful Recessive Haplotypes Identified for Fertility Traits in Nordic Holstein Cattle
Using genomic data, lethal recessives may be discovered from haplotypes that are common in the population but never occur in the homozygote state in live animals. This approach only requires genotype data from phenotypically normal (i.e. live) individuals and not from the affected embryos that die. A total of 7,937 Nordic Holstein animals were genotyped with BovineSNP50 BeadChip and haplotypes ...
متن کاملRecessive lethal mutations in Anopheles albimanus.
Six recessive lethal mutants of Anopheles albimanus are described. Homozygotes for three of the autosomal mutants, viz., bar eye, dot eye and hairy, die during the last larval or early pupal stages; complete linkage data are lacking for bar eye and hairy but dot eye is tightly linked to red eye on the right arm of chromosome 2. Larval and pupal mortality is high for homozygotes of the other two...
متن کاملIdentification of a Nonsense Mutation in CWC15 Associated with Decreased Reproductive Efficiency in Jersey Cattle
With the recent advent of genomic tools for cattle, several recessive conditions affecting fertility have been identified and selected against, such as deficiency of uridine monophosphate synthase, complex vertebral malformation, and brachyspina. The current report refines the location of a recessive haplotype affecting fertility in Jersey cattle using crossover haplotypes, discovers the causat...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Genetics Selection Evolution
سال: 2021
ISSN: 1297-9686
DOI: 10.1186/s12711-021-00634-1